Young Investigator: Lianrong Wang

Young Investigator Spotlight

Young Investigator Abstract Session - Vascular

Background: Endothelial cell (EC) maladaptation to disturbed blood flow at predilection sites of atherosclerosis is characterized by inflammation and defective regeneration. The RNase Dicer is essential for the production of microRNAs, which play a crucial role in EC maladaptation. EC-derived Dicer promotes atherosclerosis and suppresses KLF4, Notch1, and Wnt signaling. While Dicer increases EC...

Tetrahedron young investigator award 2008.

This special Symposium-in-Print issue of Bioorganic & Medicinal Chemistry Letters commemorates the 2008 Tetrahedron Young Investigator Award in Bioorganic & Medicinal Chemistry awarded to Benjamin F. Cravatt. Benjamin F. Cravatt is the Norton B Gilula Professor of Chemical Biology at The Scripps Research Institute. He received a B.S. degree in biological sciences and B.A. degree in history from...

Fims Aspetar Young Investigator Award

Every 4 years we enjoy the extraordinary abilities of Olympic athletes, wondering how many gold medals Michael Phelps will win or how fast Usain Bolt will run the 100 metres. Talking about running, as the most natural sport, with no additional equipment, have you ever wondered why there are no Europeans, Asians or even east Africans ranked among the world’s best 100 metre sprinters? Although th...

YOUNG INVESTIGATOR PERSPECTIVES Nuclear Receptor Coactivators in Neuroendocrine Function

Steroid hormones in ̄uence a variety of neuroendocrine events, including brain development, sexual differentiation and reproduction. Hormones elicit many of these effects by binding to neuronal steroid receptors, which are members of a nuclear receptor superfamily of transcriptional activators. However, the mechanisms by which activated steroid receptors regulate gene expression in brain are not...